Pandemics have afflicted civilizations throughout human history, with the earliest known outbreak occurring in 430 BC during the Peloponnesian War.
Many of these pandemics have had significant impacts on human society, from killing large percentages of the global population to causing humans to ponder larger questions about life.
Here are 10 of the most momentous pandemics that altered the course of human history, as well as coronavirus, a potential pandemic in the making.